Oxygen Tension and Formation of Cervical-Like Tissue in Two-Dimensional and Three-Dimensional Culture

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Oxygen tension and formation of cervical-like tissue in two-dimensional and three-dimensional culture.

Cervical dysfunction contributes to a significant number of preterm births and is a common cause of morbidity and mortality in newborn infants. Cervical dysfunction is related to weakened load bearing properties of the collagen-rich cervical stroma. However, the mechanisms responsible for cervical collagen changes during pregnancy are not well defined. It is known that blood flow and oxygen ten...

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ژورنال

عنوان ژورنال: Tissue Engineering Part A

سال: 2012

ISSN: 1937-3341,1937-335X

DOI: 10.1089/ten.tea.2011.0309